A case of lymphoproliferative disorder of NK-cells: aggressive immunophenotype but indolent behavior
نویسندگان
چکیده
Distinguishing chronic lymphoproliferative disorder of NK-cells from aggressive NK-cell leukemia is critical because they have distinct clinical course and management. Immunophenotyping plays a key role in distinguishing these two entities, however, it could not be used as sole criteria and clinical/laboratory findings are equally important.
منابع مشابه
Diseases of large granular lymphocytes.
BACKGROUND Clonal diseases of large granular lymphocytes (LGLs) are rare lymphoproliferative malignancies that arise from either mature T-cell (CD3+) or natural killer (NK)-cell (CD3-) lineages. They manifest a distinct biologic behavior that ranges from indolent to very aggressive. METHODS We discuss four distinct diseases involving LGLs: indolent T-cell LGL leukemia, aggressive T-cell LGL l...
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عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2015